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SQL backup failures to network share

Hello,

We recently stood up a new backup enviornment using HP StoreOnce (Deduplication applicance) as the backup target. The issue we're currently running into is when we perform a SQL backup using LiteSpeed (not compressed) to the CIFS share (\\hpeso\SQLBackups) on HP StoreOnce we get the following error:

- test backing up a 14GB database

Msg 61700, Level 16, State 1, Line 46

Backup of database "TestDatabase" failed.

Error saving data to file. Thread: 0

BACKUP DATABASE is terminating abnormally.

A nonrecoverable I/O error occurred on file "VDI_730BE351-F308-4C41-8F

C7-B6434FD61EF6_0:" 995(The I/O operation has been aborted because of either a thread exit or an application request.).

Write on "VDI_730BE351-F308-4C41-8FC7-B6434FD61EF6_0" failed: 4(The system cannot open the file.)

And when it's compressed by LiteSpeed we get a different error writing to the same backup target:

BackupIoRequest::ReportIoError: write failure on backup device 'VDI_9F406D37-986D-4A49-AA3C-844801FE9B6C_7'. Operating system error 4(The system cannot open the file.).

Is there anything I could do on the LiteSpeed configuration side in hopes to resolve this issue?

Any help in resolving this would be greatly appreciated!